2024年5月18-21號於美國華盛頓舉行的全球消化系週DDW(Digestive Disease Week)剛發表利用胃鏡，將胃底(Fundus)做黏膜燒灼以減少胃容量以及胃部飢餓素分泌的研究成果報告。
註:DDW(Digestive Disease Week)是全球肝膽腸胃科以及消化系研究最先進的一個年會
血液中飢餓素減少45%
飢餓素細胞減少53%
總體胃容量減少42%
飢餓感、食慾、對食物的渴望減少43%
總體減少8%體重平均約19磅
成功減少體重以及體內飢餓素分泌
本實驗目前在六個月的初步成果中發現，在BMI平均40，年紀在38歲的10位女性成年人中，成功減少飢餓素達45%，最大胃容量減少42%。
Key findings at six months following the procedure include:
- Patients lost approximately 8% of their body weight, an average of 9 kg.
- Plasma ghrelin levels decreased by 48% from 462 pg/mL to 255 pg/mL.
- Gastric capacity decreased by 42% from 807 mL to 467 mL.
- Histologic assessment showed a 54% reduction in ghrelin-producing cells by immunohistochemistry .
- Patient-reported hunger and Eating Drivers Index decreased significantly.
- Patient-reported control over eating, as measured by the Weight Efficacy Lifestyle Questionnaire Short-Form, increased significantly.
- The procedure was safe, with no serious adverse events.
施術時間約30-60分鐘，對於懼怕開刀後遺症、懼怕開刀後永久變更腸胃道以及不願意開刀的病人來說，將成為另一個選擇。
